The show follows Tess Foster (Torri Webster) as she copes with living in a home with just boys: her father, Jack, and three brothers, Gabe, Spencer and Sam. With the help of her best friend, Allie (Madison Pettis), she pulls through. Life with Boys is created by Michael Poryes, who also co-created Hannah Montana and That's So Raven.
It was announced that Life with Boys was renewed a second season. Shooting started on September 4, 2012, in Toronto. On February 6, 2013, the series premiered on American network TeenNick. The series ended on August 27, 2013.