The following is a list of characters featured in The Casagrandes. Please note that some of these characters have also appeared in its parent show, The Loud House.
The Santiago/Casagrande family[]
| Image | Name | Voice actor | Description | Age |
|---|---|---|---|---|
|
Ronnie Anne Santiago | Izabella Alvarez | Lincoln's second best friend, love interest and Bobby's younger sister, who enjoys skating and pranks. | 11 (S1) 12 (S2-onwards) |
 |
Bobby Santiago | Carlos Pena, Jr. | Lori's boyfriend, who is normally seen texting or calling her. He works in his family's bodega downstairs. | 17 (S1) 18 (S2-onwards) |
 |
Maria Santiago | Sumalee Monatano | Bobby and Ronnie Anne's mother, who works as a nurse at the Great Lakes City hospital. | 43 |
 |
Arturo Santiago | Eugenio Derbez | Maria's ex-husband/husband, and Bobby and Ronnie Anne's father, who worked as a doctor in Peru but then moved to Great Lakes City to live and stay permanently with his family and his kids. | 44 |
 |
Rosa Casagrande | Sonia Manzano | Ronnie and Bobby's grandmother, who manages the apartment building in which the Casagrandes live and has many remedies. | 63 |
 |
Hector Casagrande | Ruben Garfias | Bobby and Ronnie's grandfather, who runs the bodega located on the first floor of the apartment building. | 66 67 (turned in S4 E4A) |
 |
Carlos Casagrande | Carlos Alazraqui | Ronnie and Bobby's bibliophilic and absent-minded uncle who teaches at a university in Great Lakes City. His first name is named after his voice actor. | 45 |
 |
Frida Puga Casagrande | Roxanna Ortega | Bobby and Ronnie's aunt, who is overemotional and constantly taking photos. | 42 |
 |
Carlota Casagrande | Alexa PenaVega | The oldest of the Casagrande kids who loves fashion and goes live about her tips. | 17 |
 |
CJ Casagrande | Jared Kozak | The second oldest of the Casagrande kids who loves to play pirates and has Down Syndrome. | 13 |
 |
Carl Casagrande | Alex Cazares | The second youngest of the kids, who acts like a wannabe Lothario and thinks he's super cool. | 8 |
 |
Carlitos Casagrande | Roxana Ortega (2017-2019) Cristina Milizia (current) |
The youngest in the family, who is a year older than Lily Loud. | 1 |
 |
Lalo | Dee Bradley Baker | The Casagrande family's pet mastiff dog. | TBA |
 |
Sergio | Carlos Alazraqui | The Casagrande family's pet parrot who doesn't repeat words - he answers back. | TBA |
The Chang family[]
| Image | Name | Voice actor | Description | Age |
|---|---|---|---|---|
 |
Sid Chang | Leah Mei Gold | Ronnie Anne’s best friend who moved to the city and wants to try anything in the new city. | 12 |
 |
Adelaide Chang | Lexi Sexton | Sid's little sister. | 6 |
 |
Stanley and Becca Chang | Ken Jeong and Melissa Joan Hart | Sid and Adelaide's parents. | Stanley: 42 Becca: 41 |
 |
Breakfast Bot | Carlos Alazraqui | A cooking robot built by Sid. | N/A |
Other recurring characters[]
| Image | Name | Voice actor | Description | Age |
|---|---|---|---|---|
 |
Nikki, Casey and Sameer | Natalie Coughlin, Christian Simon, and Makana Say | Three friends of Ronnie Anne and Sid. | TBA |
 |
Laird | Sean Kenin | A rather clumsy, unlucky classmate of Ronnie Anne and Sid's. | 10 |
 |
Vito Filliponio | Carlos Alazraqui | A frequent customer at the Casagrande Mercado. | 70 |
 |
Becky | Abby Trott | A classmate of Ronnie Anne, she is a feisty blonde girl who enjoys lucha libre and dodgeball, and is dating a female classmate named Dodge. | TBA |
 |
Par | Sunil Malhotra | The Casagrande family's fun-loving, thrill-seeking delivery man, and Bobby's best friend, who delivers produce to the Mercado and also teaches karate. | 19-20 |
 |
Maybelle | Telma Hopkins | A frequent, very picky customer at the Casagrade Mercado. | TBA |
 |
Miranda | Cristina Pucelli | A resident of the Casagrande Apartment who lives in room 4D, who likes to play hacky sack. | TBA |
 |
Mr. Nakamura | Bruce Locke | 46 | |
 |
Georgia | Shondlia White | A resident of the Casagrande Apartment, who builds houses of cards. | TBA |
 |
Mrs. Kernicky | Lauri Fraser | An kindly old woman who lives in the apartment above the Changs'. She enjoys exercising and became Cesar Chavez Academy's new gym teacher at the end of Season 2. | TBA |
 |
Margarita | Krizia Bajos | A woman who runs her own beauty salon called Margarita's Beauty. | 35 |
 |
Bruno | Eric Bauza | Great Lakes City's local hot-dog vendor. | TBA |
 |
Diego | TBA | An ex-boyfriend of Carlota. | 17 |
Minor characters[]
| Image | Name | Voice actor | Description | Age |
|---|---|---|---|---|
 |
Street Cats | Unknown | A stray black cats who terrorizing people and causing chaos across the city. They are Mr. Wiggles' minions and the Casagrandes' arch-nemesis. | TBA |
 |
Mr. Wiggles | Dee Bradley Baker | A stray cat who is the leader of the street cats. He is also a king of the alley. | TBA |
 |
City Rats | Unknown | A rats who terrorizing humans. In "My Fair Cat Lady", they reveals their leader. | TBA |
 |
Rat Leader | Unknown | A leader of the city rats. | TBA |