Unlike Phred on Your Head Show, the show focuses on user-submitted content (often artwork presented through Noggin.com). The URL in the series' title is stated by Phred to stand for "U R Live," in addition to referencing the show's focus on Web content.
Phred hosts a televised art showcase in between viewings of other Noggin shows.
The show is hosted by Phred, a former pickle mascot who lives in the dot of Noggin.com. His co-hosts are two alien creatures, both named Skengle, who originated in a Noggin.com game titled "Skengle 2.0" in 2000. Big Voice, a commanding voice belonging to an unseen human, also plays a prominent role in the show.
Data such as high scores for videogames on Noggin.com would air along with the focused content. User-submitted content such as "Dress Phred" (a "dress-up" videogame in which the player chooses an outfit for Phred to wear), poll results (presented by the Skengles), and "Noggimation" animated patches were often featured.